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Monoclonal Anti-Influenza A virus (A/Darwin/9/2021) NA (H3N2) Antibody, Human IgG1 (8B5) (MALS verified)

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Product Number/Spec
Price
Menge
NEE-MY2392-100ug
$350.00
NEE-MY2392-1mg (250ug X 4)
$2310.00
ETA of in-stock products:2 business days
Gesamtanzahl Product Amount$ 0

Product Details

  • Source

    Monoclonal Anti-Influenza A virus (A/Darwin/9/2021) NA (H3N2) Antibody, Human IgG1 (8B5) is a recombinant chimeric monoclonal antibody expressed in HEK293, which combines the variable region of a mouse monoclonal antibody with human constant domain.

  • Antibody Type

    Recombinant Monoclonal

  • Clone

    8B5

  • Isotype

    Human IgG1, Kappa

  • Host Species

    Mouse

  • Reactivity

    Virus

  • Immunogen

    Recombinant Influenza A [A/Darwin/9/2021 (H3N2)] Neuraminidase (NA) Protein is expressed from human 293 cells

  • Specificity

    Specifically recognizes Influenza A [A/Darwin/9/2021 (H3N2)] Neuraminidase (NA) Protein; Has cross-reactivity in ELISA with: Influenza A [Darwin/6/2021] Neuraminidase NA(H3N2) Protein, Influenza A virus (A/Thailand/8/2022) NA(H3N2) Protein, Influenza A virus (A/Croatia/10136RV/2023) & (A/District of Columbia/27/2023) NA(H3N2) Protein, Influenza A virus (A/Massachusetts/18/2022) NA(H3N2) Protein.

  • Application

    Application
    Recommended Usage
    ELISA
    0.2-2 μg/mL
  • Cross Verification

    This product No cross-reactivity in ELISA with
    Influenza B [PHUKET/3073/2013] Neuraminidase (NA) Protein, His Tag (Cat. No. NEE-V5246).
    Influenza B [Austria/1359417/2021] Neuraminidase (NA) Protein, His Tag (Cat. No. NEE-V5245).
    Influenza A [Sydney/5/2021] Neuraminidase (NA) Protein, His Tag (Cat. No. NEE-V5248).
    Influenza A [A/Thailand/1(KAN-1)/2004(H5N1)] Neuraminidase (NA) Protein, His Tag (Cat. No. HA1-V5245).
    Influenza A [Guangdong/18SF020(H5N6)] Neuraminidase (NA) Protein, His Tag (Cat. No. NEE-V524h).
    Influenza A [turkey/Germany-MV/R2472/2014(H5N8)] Neuraminidase (NA) Protein, His Tag (Cat. No. NEE-V5249).
    Influenza A [Wisconsin/588/2019(H1N1)] Neuraminidase (NA) Protein, His Tag (Cat. No. NEE-V524k).
    Influenza A [Victoria/2570/2019(H1N1)] Neuraminidase (NA) Protein, His Tag (Cat. No. NEE-V524e).
    Influenza A [Wisconsin/67/2022(H1N1)] Neuraminidase (NA) Protein, His Tag (Cat. No. NEE-V524m).

  • Purification

    Protein A purified / Protein G purified.

  • Aggregation

    Less than 10%, as determined by SEC-MALS.

  • Concentration

    Please refer to the Certificate of Analysis (CoA).

  • Form

    Lyophilized

  • Formulation

    Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

    Please contact us for customized product forms or formulations.

  • Reconstitution

    Please refer to the Certificate of Analysis (CoA) for specific instructions.

  • Shipping

    Lyophilized product is shipped at ambient temperature.

  • Storage

    For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Notices

    Product Specific Notices: For research use only.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Data Display

  • Bioactivity-ELISA

     Neuraminidase/NA (Influenza Virus) ELISA

    Immobilized Influenza A [A/Darwin/9/2021 (H3N2)] Neuraminidase (NA) Protein, His Tag (Cat. No. NE2-V5249) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Influenza A virus (A/Darwin/9/2021) NA (H3N2) Antibody, Human IgG1 (8B5) (Cat. No. NEE-MY2392) with a linear range of 0.06-2 ng/mL (QC tested).

    Protocol
  •  Neuraminidase/NA (Influenza Virus) ELISA

    Immobilized Influenza A [Darwin/6/2021] Neuraminidase (NA) Protein, His Tag (Cat. No. NEE-V5247) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Influenza A virus (A/Darwin/9/2021) NA (H3N2) Antibody, Human IgG1 (8B5) (Cat. No. NEE-MY2392) with a linear range of 0.05-2 ng/mL (Routinely tested).

    Protocol

User Reviews
Publish Comment

Background Introduction

Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Neuraminidase, on the other hand, cleaves the HA-sialic acid bondage from the newly formed virions and the host cell receptors during budding. Neuraminidase thus is described as a receptor-destroying enzyme which facilitates virus release and efficient spread of the progeny virus from cell to cell.

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