user
menu
letter
Sign InRegister
langEnglisharrow

Cat. No. / Size
Price
Availability
Qty
IFN-BS138-25ug
$415.00
Inquire about delivery time
IFN-BS138-200ug
$1,635.00
Inquire about delivery time
IFN-BS138
Sub-Total :
$ 0
Customize Product Request Quote
Contact Us
Contact Us
Sub-Total:
$ 0
Request Quote
  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources

  • 抗体来源（Source）

    Biotinylated Monoclonal Anti-IFNγ Antibody, Mouse IgG1 (13E6H6) is a Mouse monoclonal antibody produced from a hybridoma created by fusing SP2/0 myeloma and Mouse B-lymphocytes.

  • 克隆号（Clone）

    13E6H6

  • 种属（Species）

    Mouse

  • 亚型（Isotype）

    Mouse IgG1 | Mouse Kappa

  • 偶联（Conjugate）

    Biotin

  • 抗体类型（Antibody Type）

    Hybridoma Monoclonal

  • 种属反应性（Reactivity）

    Human

  • 免疫原（Immunogen）

    Recombinant Human IFNγ is expressed from human HEK293 cells.

  • 特异性（Specificity）

    This product is a specific antibody specifically reacts with IFN-γ, Human. No cross-reactivity is detected with other human cytokines, including IL-2, IL-4, IL-6, IL-10, GM-CSF and TNF-alpha.

  • 应用（Application）

    Application
    Recommended Usage
    ELISA
    0.2-50 mg/mL

  • 纯度（Purity）

    95% as determined by SDS-PAGE.

    90% as determined by SEC-MALS.

  • 纯化（Purification）

    Protein A purified / Protein G purified

  • 制剂（Formulation）

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 重构方法（Reconstitution）

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • 存储（Storage）

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.

  • 质量管理控制体系（QMS）

    1. 质量管理体系（ISO, GMP）
    2. 质量优势
    3. 质控流程

Background

Interferon-gamma (IFN-γ/IFNG) is a dimerized soluble cytokine that is the only member of the type II class of interferon. This interferon was originally called macrophage-activating factor, a term now used to describe a larger family of proteins to which IFN-γ belongs. IFN-gamma has been used in a wide variety of clinical indications. Interferon-gamma (IFNgamma) is a central regulator of the immune response and signals via the Janus Activated Kinase (JAK)-Signal Transducer and Activator of Transcription (STAT) pathway. Interferon gamma has broader roles in activation of innate and adaptive immune responses to viruses and tumors, in part through upregulating transcription of genes involved in cell cycle regulation, apoptosis, and antigen processing/presentation. Despite this, rodent and human trophoblast cells show dampened responses to IFNG that reflect the resistance of these cells to IFNG-mediated activation of major histocompatibility complex (MHC) class II transplantation antigen expression.