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Product Details
Background
Recombinant Monoclonal Anti-HER2 Antibody, Rabbit (5D5) is a HER2 primary antibody for IHC application. Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone.
Product Specifications
Host SpeciesRabbitIsotypeRabbit IgG, Rabbit KappaClone5D5ApplicationIHC-PDilution Ratio1: 500 - 1: 2000FormLiquidClonalityMonoclonalReactivityHumanSynonymsERBB2Concentration0.9~1.1 mg/mlSpecificityReact with HER2 protein on the membrane of target cell/tissuePurification TechProtein APreservationPBS, BSA, GlycerolExperiment Protocol
Storage
Shipped at 4°C, Blue Ice. Store at +4°C for short term (1-2 weeks). Store at -20°C for long term.
Avoid freeze / thaw cycle. Upon delivery aliquot.ACRO Quality Management System
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Performance Data
Sample Staining Data
Immunohistochemical analysis of paraffin embedded human breast cancer tissue labelled with HGS-S254 at 1:1000 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with LEICA BOND IHC staining protocol.
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Drug Development Progress- English Name：
Receptor protein-tyrosine kinase erbB-2
- Category：
- Approved Drugs：
47 Details
- Drugs in Clinical Trials：
238 Details
- Highest Development Stage：
Approved
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