Monoclonal Anti-Glycoprotein H & Glycoprotein L/gH & gL (HSV) (HSV-1, strain 17) Antibody, Human IgG1 (4D10)

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GHL-MY2274-100ug
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GHL-MY2274-1mg (500ug X 2)
$2,310.00
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Source

Monoclonal Anti-Glycoprotein H & Glycoprotein L/gH & gL (HSV) (HSV-1, strain 17) Antibody, Human IgG1 (4D10) is recombinantly expressed in HEK293. It consists of mouse variable regions genetically fused to human constant domains.

Antibody Type

Recombinant Monoclonal

Clone

4D10

Isotype

Human IgG1, Kappa

Host Species

Mouse

Reactivity

virus

Immunogen

Recombinant HSV-1 (strain 17) gH&gL Protein is expressed from human 293 cells

Specificity

Specifically recognizes HSV-1 (strain 17) gH&gL Protein.

Application
Application
Recommended Use
Western Blot
0.02 μg/mL
ELISA
0.2-2 μg/mL

* Recommended dilutions are for reference only. Optimal working concentrations may vary depending on your consumables, reagents, and assay conditions. We recommend optimizing for your specific system. No warranty is made regarding performance at any specific dilution.

Purification

Protein A purified.

Aggregation

Less than 10%, as determined by SEC-MALS.

Concentration

Please refer to the Certificate of Analysis (CoA).

Form

Lyophilized

Formulation

Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

Please contact us for customized product forms or formulations.

Reconstitution

Please refer to the Certificate of Analysis (CoA) for specific instructions.

Shipping

Lyophilized product is shipped at ambient temperature.

Storage

For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • -20°C to -70°C for 12 months in lyophilized state;
  • -70°C for 3 months under sterile conditions after reconstitution.
Notices

Product Specific Notices: For research use only.

Background

The herpes simplex virus type 1 (HSV-1) gH-gL complex which is found in the virion envelope is essential for virus infectivity and is a major antigen for the host immune system.The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis.