HRP conjugated Monoclonal Anti-Eribulin Antibody, Rabbit IgG (1M1G11)

Antibody Internalization Detection Reagent (IGG-PZF2001) monitors endocytosis in live cells
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ERN-PLM12b-25ug
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Source

HRP conjugated Monoclonal Anti-Eribulin Antibody, Rabbit IgG (1M1G11) is a recombinant rabbit monoclonal antibody expressed in HEK293 cells.

Antibody Type

Recombinant Monoclonal

Clone

1M1G11

Isotype

Rabbit IgG, Kappa

Host Species

Rabbit

Conjugate

HRP conjugated

Specificity

This product is a specific antibody specifically reacts with Eribulin.

Application
Application
Recommended Use
ELISA
1:200-1:2000

* Recommended dilutions are for reference only. Optimal working concentrations may vary depending on your consumables, reagents, and assay conditions. We recommend optimizing for your specific system. No warranty is made regarding performance at any specific dilution.

Purification

Protein A purified.

Concentration

Please refer to the Certificate of Analysis (CoA).

Form

Lyophilized

Formulation

Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

Please contact us for customized product forms or formulations.

Reconstitution

Please refer to the Certificate of Analysis (CoA) for specific instructions.

Shipping

Lyophilized product is shipped at ambient temperature.

Storage

For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

Please protect from light and avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • -20°C to -70°C for 12 months in lyophilized state;
  • -70°C for 3 months under sterile conditions after reconstitution.
Notices

Product Specific Notices: For research use only.

Background Introduction

Eribulin is a synthetic analogue of the macrocyclic polyether halichondrin B, which was originally isolated from the Asian sea sponge Halichondria okadai. Eribulin binds specifically to the β-tubulin subunit on the (+) end of the microtubule and potently inhibits elongation of the formed microtubule, while having little or no effect on microtubule depolymerization. Eribulin's potent antimitotic activity and nonmitotic effects on tumor biology make it an interesting candidate for investigation as a MTA payload for ADCs.