Mein Warenkorb

Monoclonal Anti-Monkeypox-E8L Antibody, Human IgG1 (1C12) (MALS verified)

User Reviews
Product Number/Spec
Price
Menge
E8L-M573-100ug
$435.00
E8L-M573-1mg (500ug X 2)
$2890.00
ETA of in-stock products:2 business days
Gesamtanzahl Product Amount$ 0

Product Details

  • Source

    Monoclonal Anti-Monkeypox-E8L Antibody, Human IgG1 (1C12) is a recombinant chimeric monoclonal antibody expressed in HEK293, which combines the variable region of a mouse monoclonal antibody with human constant domain.

  • Antibody Type

    Recombinant Monoclonal

  • Clone

    1C12

  • Isotype

    Human IgG1, Kappa

  • Host Species

    Mouse

  • Reactivity

    Virus

  • Immunogen

    Recombinant Monkeypox virus (strain Zaire-96-I-16) E8 derived from human 293 cells

  • Specificity

    This product is a specific antibody specifically reacts with E8L (MPXV).

  • Application

    Application
    Recommended Usage
    ELISA
    0.2-2 μg/mL
  • Purification

    Protein A purified / Protein G purified.

  • Aggregation

    Less than 10%, as determined by SEC-MALS.

  • Concentration

    Please refer to the Certificate of Analysis (CoA).

  • Form

    Lyophilized

  • Formulation

    Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

    Please contact us for customized product forms or formulations.

  • Reconstitution

    Please refer to the Certificate of Analysis (CoA) for specific instructions.

  • Shipping

    Lyophilized product is shipped at ambient temperature.

  • Storage

    For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Notices

    Product Specific Notices: For research use only.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

Kunden haben auch angesehen

Data Display

  • Bioactivity-ELISA

     E8L (MPXV) ELISA

    Immobilized Monkeypox virus (strain Zaire-96-I-16) E8L, His Tag (Cat. No. E8L-M52H3) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Monkeypox-E8L Antibody, Human IgG1 (1C12) (Cat. No. E8L-M573) with a linear range of 0.1-2 ng/mL (QC tested).

    Protocol
  • Bioactivity-SPR

     E8L (MPXV) SPR

    Monoclonal Anti-Monkeypox-E8L Antibody, Human IgG1 (1C12) (Cat. No. E8L-M573) captured on Protein A Chip can bind Monkeypox virus (strain Zaire-96-I-16) E8L, His Tag (Cat. No. E8L-M52H3) with an affinity constant of 0.119 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

    Protocol

User Reviews
Publish Comment

Background Introduction

Monkeypox is a rare zoonosis caused by monkeypox virus, which has become the most serious orthpoxvirus and consists of complex double stranded DNA. The pathogenesis of monkeypox is that the virus invades the body from respiratory mucosa , multiplies in lymphocytes, and incurs into blood producing transient venereal toxemia. after the virus multiplies in cells, the cells can invade the blood and propagate to the skin of the whole body, causing lesions. E8L can Binds to chondroitin sulfate on the cell surface to provide virion attachment to target cell.

Frontier Progress

 
Drug Candidate Licensing
More
  • Basic Product Information
  • Product Details
  • Kunden haben auch angesehen
  • Data Display
  • User Reviews
  • Hintergrund
Kontaktieren Sie uns