Mein Warenkorb

Biotinylated Anti-DXD&Exatecan Antibody, Mouse IgG1, Avitag™

  • Antibody Internalization Detection Reagent (IGG-PZF2001) monitors endocytosis in live cells
User Reviews
Product Number/Spec
Price
Menge
DXD-BVM807-25ug
$705.00
DXD-BVM807-200ug
$4920.00
ETA of in-stock products:2 business days
Gesamtanzahl Product Amount$ 0

Product Details

  • Source

    Biotinylated Anti-DXD&Exatecan Antibody, Mouse IgG1, Avitag is a recombinant mouse monoclonal antibody expressed in HEK293 cells.

  • Antibody Type

    Recombinant Monoclonal

  • Isotype

    Mouse IgG1, Kappa

  • Immunogen

    DXD

  • Conjugate

    Biotin

  • Specificity

    Specifically recognizes the target-DXD.

  • Application

    Application
    Recommended Usage
    ELISA
    1:100-1:1000
  • Purification

    Protein A purified / Protein G purified.

  • Concentration

    Please refer to the Certificate of Analysis (CoA).

  • Form

    Lyophilized

  • Formulation

    Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

    Please contact us for customized product forms or formulations.

  • Reconstitution

    Please refer to the Certificate of Analysis (CoA) for specific instructions.

  • Shipping

    Lyophilized product is shipped at ambient temperature.

  • Storage

    For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Notices

    Product Specific Notices: For research use only.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

Kunden haben auch angesehen

Data Display

  • Bioactivity-ELISA

     DXD ELISA

    Immobilized Human Her2, His Tag (Cat. No. HE2-H5225) at 1 μg/mL, add Trastuzumab Deruxtecan in the 100% Human Serum and then add Biotinylated Anti-DXD&Exatecan Antibody, Mouse IgG1, Avitag (Cat. No. DXD-BVM807) at 0.05 μg/mL. Detection was performed using HRP-conjugated Streptavidin (Acro, Cat. No. STN-NH913) (QC tested).

    Protocol
  •  DXD ELISA

    Immobilized Trastuzumab Deruxtecan at 1 μg/mL (100 μL/well) can bind Biotinylated Anti-DXD&Exatecan Antibody, Mouse IgG1, Avitag (Cat. No. DXD-BVM807) with a linear range of 0.5-8 ng/mL (Routinely tested).

    Protocol

User Reviews
Publish Comment

Background Introduction

DXD (Exatecan derivative) is a potent DNA topoisomerase I inhibitor and is widely used as a cytotoxic payload of antibody-drug conjugates (ADCs) for the treatment of multiple cancers. Anti-DXD antibody is a mouse monoclonal antibody. This antibody has been validated for use in PK, PD, immunoassays, and ELISA.

Frontier Progress

 
Drug Candidate Licensing
More
  • Basic Product Information
  • Product Details
  • Kunden haben auch angesehen
  • Data Display
  • User Reviews
  • Hintergrund
Kontaktieren Sie uns