Monoclonal Anti-Claudin-18.2 Antibody, Mouse IgG1 (3B10)

描述/背景（Background）

The Claudin-18.2 (CLDN 18.2) protein, an isoform of Claudin 18, a member of the tight junction protein family, is a highly selective biomarker with limited expression in normal tissues and often abnormal expression during the occurrence and development of various primary malignant tumors, such as gastric cancer/gastroesophageal junction (GC/GEJ) cancer, breast cancer, colon cancer, liver cancer, head and neck cancer, bronchial cancer and non-small-cell lung cancer. Claudin-18.2 participates in the proliferation, differentiation and migration of tumor cells. Recent studies have identified Claudin-18.2 expression as a potential specific marker for the diagnosis and treatment of these tumors.

种属（Host Species）

Mouse

克隆号（Clone）

3B10

适用方法（Application）

IHC

效价（Property）

1：1000

状态（State）

Liquid

阳性对照（Positive Control）

Human Stomach Tissues

克隆类型（Clonality）

Monoclonal

分子别名（Synonym）

Claudin18.2, CLDN 18.2

研究领域（Research Field）

Cancer Drug Targets

抗体来源（Source）

Mouse

同种型（Isotype）

IgG

储存（Storage）

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.