PerCP-Cy5.5 Labeled Monoclonal Anti-Human CD45 Antibody, Mouse IgG2a

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Clone

AS225

Isotype

Mouse IgG2a, Kappa

Host Species

Mouse

Reactivity

Human

Conjugate

PerCP-Cy5.5

Excitation Wavelength: 488 nm

Emission Wavelength: 690 nm

Specificity

This product is a specific antibody specifically reacts with CD45 protein.

Application

This PerCP-Cy5.5-CD45 Antibody is specifically developed for flow cytometry applications to detect the expression of CD45 on human cells. Additionally, the Human TBNK 6-color Cocktail Flow Panel kit (Cat. No. ICA-A001) is available, with the PerCP-Cy5.5-CD45 Antibody being one component of the kit.

Recommended Dilution

1:20

Form

Liquid

Formulation

Supplied as 0.2 μm-filtered solution in PBS (pH 7.4) containing 0.03% ProClin 300 and 0.2% BSA, with trehalose as protectant.

Please contact us for customized product forms or formulations.

Shipping

Liquid product is shipped at blue ice.

Storage

Please protect from light and avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • Store at 2-8 °C for 12 months.
Notices

Product Specific Notices: For research use only.

Background Introduction

CD45 is a receptor protein tyrosine phosphatase, also known as Ly-5 or leukocyte common antigen. CD45 mainly involves in the initiation of T cell receptor signaling by controlling the activation of the Src family protein-tyrosine kinases Lck and Fyn. CD45 deficiency causes in T- and B-lymphocyte dysfunction in the form of severe combined immune deficiency. It also takes a significant role in autoimmune diseases and cancer as well as in infectious diseases including fungal infections.