PerCP-Cy5.5 Labeled Monoclonal Anti-Human CD45 Antibody, Mouse IgG2a

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FABm007-06-50tests
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Source

PerCP-Cy5.5 Labeled Monoclonal Anti-Human CD45 Antibody, Mouse IgG2a is a recombinant mouse monoclonal antibody expressed in - cells.

Antibody Type

Recombinant Monoclonal

Clone

AS225

Isotype

Mouse IgG2a, Kappa

Host Species

Mouse

Reactivity

Human

Conjugate

PerCP-Cy5.5

Excitation Wavelength: 488 nm

Emission Wavelength: 690 nm

Specificity

This product is a specific antibody specifically reacts with CD45 protein.

Application
Application
Recommended Use
Flow Cytometry
1:20

* Recommended dilutions are for reference only. Optimal working concentrations may vary depending on your consumables, reagents, and assay conditions. We recommend optimizing for your specific system. No warranty is made regarding performance at any specific dilution.

Concentration

Please refer to the Certificate of Analysis (CoA).

Form

Liquid

Formulation

Supplied a 0.22 μm-filtered solution in PBS (pH 7.4) containing 0.03% ProClin 300 and 0.2% BSA, with trehalose as protectant.

Please contact us for customized product forms or formulations.

Shipping

Liquid product is shipped at blue ice.

Storage

Please protect from light and avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • Store at 2-8 °C for 12 months.
Notices

Product Specific Notices: For research use only.

Background Introduction

CD45 is a receptor protein tyrosine phosphatase, also known as Ly-5 or leukocyte common antigen. CD45 mainly involves in the initiation of T cell receptor signaling by controlling the activation of the Src family protein-tyrosine kinases Lck and Fyn. CD45 deficiency causes in T- and B-lymphocyte dysfunction in the form of severe combined immune deficiency. It also takes a significant role in autoimmune diseases and cancer as well as in infectious diseases including fungal infections.

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