PE-CY7-Labeled Monoclonal Anti-Human CD4 Antibody, Mouse IgG1 (8C3)

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FABm002-04-50tests
$200.00
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Source

Monoclonal Anti-Human CD4 Antibody, Mouse IgG1 (8C3) is a mouse monoclonal antibody produced from hybridoma.

Antibody Type

Hybridoma Monoclonal

Clone

8C3

Isotype

Mouse IgG1, Kappa

Host Species

Mouse

Reactivity

Human

Immunogen

Purified Human CD4 Protein

Conjugate

PE-CY7

Excitation Wavelength: 561 nm

Emission Wavelength: 780 nm

Specificity

This product is a specific antibody specifically reacts with CD4 protein.

Application
Application
Recommended Use
Flow Cytometry
1:20

* Recommended dilutions are for reference only. Optimal working concentrations may vary depending on your consumables, reagents, and assay conditions. We recommend optimizing for your specific system. No warranty is made regarding performance at any specific dilution.

Concentration

Please refer to the Certificate of Analysis (CoA).

Form

Liquid

Formulation

Supplied a 0.22 μm-filtered solution in PBS (pH 7.4) containing 0.03% ProClin 300 and 0.2% BSA, with trehalose as protectant.

Please contact us for customized product forms or formulations.

Shipping

Liquid product is shipped at blue ice.

Storage

Please protect from light and avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • Store at 2-8 °C for 12 months.
Notices

Product Specific Notices: For research use only.

Background Introduction

T-cell surface glycoprotein CD4 is also known as T-cell surface antigen T4/Leu-3. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is accessory protein for MHC class-II antigen/T-cell receptor interaction. CD4 induces the aggregation of lipid rafts. CD4 is a primary receptor used by HIV-1 to gain entry into host T cells. HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors. Therefore, medical professionals refer to the CD4 count to decide when to begin treatment for HIV-infected patients.

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