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Product Details
Background
Recombinant Monoclonal Anti-CD31 Antibody, Mouse (1G6) is a CD31 primary antibody for IHC application. CD31 is expressed on platelets and on most leukocytes and is constitutively present on endothelial linings in vivo. CD31 mediates adhesion through homophilic interaction; however, a heparin-binding consensus sequence (LKREKN) on domain 2 may mediate heterophilic interaction with cell-surface or extracellular matrix proteoglycans.
Product Specifications
Host SpeciesMouseIsotypeMouse IgGClone1G6ApplicationIHC-PDilution Ratio1: 500 - 1: 2000FormLiquidClonalityMonoclonalReactivityHumanSynonymsPECAM-1Concentration0.9~1.1 mg/mlSpecificityReact with CD31 protein on the membrane of target cell/tissuePurification TechProtein APreservationTris buffer, 1% BSAExperiment Protocol
Storage
Shipped at 4°C, Blue Ice. Store at +4°C for short term (1-2 weeks). Store at -20°C for long term.
Avoid freeze / thaw cycle. Upon delivery aliquot. The shelf life is 30 days from the date of opening.ACRO Quality Management System
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Performance Data
Sample Staining Data
Immunohistochemical analysis of paraffin embedded human cancer tissue labelled with HGS-S245 at 1/1000 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
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