FMC63 scFv, His Tag (MALS verified)

Cat. No. / Size
Price
Qty
CD9-M52Hb-100ug
$225.00
CD9-M52Hb-1mg (500ug X 2)
$1635.00
ETA of in-stock products:2 business days

Product Details

  • Source

    FMC63 scFv, His Tag is a recombinant single-chain variable fragment derived from the mouse monoclonal antibody clone FMC63 and expressed in HEK293 cells.

  • Antibody Type

    Recombinant Monoclonal

  • Host Species

    Mouse

  • Reactivity

    Human

  • Immunogen

    CD19

  • Specificity

    Specifically recognizes the CD19.

  • Application

    Application
    Recommended Usage
    ELISA
    1:100-1:1000
  • Purification

    Affinity purification.

  • Aggregation

    Less than 5%, as determined by SEC-MALS.

  • Concentration

    Please refer to the Certificate of Analysis (CoA).

  • Form

    Lyophilized

  • Formulation

    Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

    Please contact us for customized product forms or formulations.

  • Reconstitution

    Please refer to the Certificate of Analysis (CoA) for specific instructions.

  • Shipping

    Lyophilized product is shipped at ambient temperature.

  • Storage

    For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Notices

    Product Specific Notices: For research use only.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

Customers Also Viewed

Performance Data

  • Bioactivity-ELISA

     CD19 ELISA

    Immobilized Human CD19 (20-291), Fc Tag, premium grade (Cat. No. CD9-H5251) at 5 μg/mL (100 μL/well) can bind FMC63 scFv, His Tag (Cat. No. CD9-M52Hb) with a linear range of 0.005-0.156 μg/mL (QC tested).

    Protocol

Customer Reviews
Writing Reviews

Background

FMC63 is an IgG2a mouse monoclonal antibody specific for CD19, which is a target for the immunotherapy of B lineage leukaemias and lymphomas. FMC63 scFv is the most commonly used ectodomain component of CD19-specific CARs. So far, most of reported CART19 trials contain the anti-CD19 scFv derived from FMC63, including the two FDA-approved CARs Kymriah and Yescarta.

Recent Advances

 
Drug Development Progress
  • English Name:

    B-lymphocyte antigen CD19

  • Category:

  • Approved Drugs:

    14 Details

  • Drugs in Clinical Trials:

    435 Details

  • Highest Development Stage:

    Approved

Drug Candidate Licensing
More
  • Basic Product Information
  • Product Details
  • Customers Also Viewed
  • Performance Data
  • Customer Reviews
  • Background