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PE-CY7-Labeled Monoclonal Anti-Human CD105 Antibody, Rabbit IgG (AS674) (0.03% Proclin)

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FABr067-04-200tests (50tests X 4)
$600.00
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FABr067-04
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Product Details
Performance Data
Reviews & Citations
Resources
  • Product Details
  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources
Source

Monoclonal Anti-Human CD105 Antibody, Rabbit IgG (AS674) is a rabbit monoclonal antibody, which provides higher batch consistency and long term security of supply.

Clone

AS674

Isotype

Rabbit IgG, Kappa

Host Species

Rabbit

Reactivity

Human

Immunogen

Purified Human CD105 Protein

Conjugate

PE-CY7

Excitation Wavelength: 561 nm

Emission Wavelength: 780 nm

Specificity

This product is a specific antibody specifically reacts with CD105 protein.

Application
Application
Recommended Use
Flow Cytometry
1:20

* Recommended dilutions are for reference only. Optimal working concentrations may vary depending on your consumables, reagents, and assay conditions. We recommend optimizing for your specific system. No warranty is made regarding performance at any specific dilution.

Concentration

Please refer to the Certificate of Analysis (CoA).

Form

Liquid

Formulation

Supplied a 0.22 μm-filtered solution in PBS (pH 7.4) containing 0.03% ProClin 300 and 0.2% BSA, with trehalose as protectant.

Please contact us for customized product forms or formulations.

Shipping

Liquid product is shipped at blue ice.

Storage

Please protect from light and avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • Store at 2-8 °C for 12 months.
Notices

Product Specific Notices: For research use only.

ACRO Quality Management System

Background

CD105, also known as Endoglin, is a ~180 kDa type I integral membrane homodimeric glycoprotein (90 kDa per subunit) and a core positive marker for mesenchymal stem cell (MSC) identification via flow cytometry. It is highly expressed on vascular endothelial cells, placental syncytiotrophoblasts, activated monocytes and tissue macrophages, with weak expression on stromal fibroblasts, and upregulated in activated endothelium during angiogenesis (e.g., tumors, wound healing, dermal inflammation). As a key component of the TGF-β receptor system, it binds TGF-β1/β3 with high affinity (not TGF-β2), participates in TGF-β signaling and angiogenesis pathways to regulate endothelial proliferation, migration and vascular remodeling, serving as a vital target for MSC identification, vascular and tumor-related flow cytometry studies. The specific CD105 flow antibody facilitates accurate detection and analysis of target cells, thereby accelerating research progress in stem cell biology, angiogenesis and tumor pathogenesis.

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