Gastrin-71

Gastrin-71 Overview

English NameGastrinsApproved Drugs0
Drugs in Clinical Trials0Target SynonymGastrins
Highest Development StageDiscontinued
English NameGastrins
Target SynonymGastrins
Approved Drugs0
Drugs in Clinical Trials0
Highest Development StageDiscontinued

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Gastrin-71 Background

Gastrin is a peptide hormone that stimulates secretion of gastric acid (HCl) by the parietal cells of the stomach and aids in gastric motility. It is released by G cells in the pyloric antrum of the stomach, duodenum, and the pancreas. Gastrin binds to cholecystokinin B receptors to stimulate the release of histamines in enterochromaffin-like cells, and it induces the insertion of K+/H+ ATPase pumps into the apical membrane of parietal cells (which in turn increases H+ release into the stomach cavity). Its release is stimulated by peptides in the lumen of the stomach.

Gastrin-71 Synonyms

Gastrin-71,Gastrin,GAST,Gastrin component
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