BMP-10

Produktanfrage

Klinische Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Indikationen	Klinische Studie
Veligrotug	ZB-001; VRDN-001; AVE-1642	Phase 3 Clinical	Viridian Therapeutics Inc	Solid tumours; Graves Ophthalmopathy; Multiple Myeloma; Breast Neoplasms	Details
Ganitumab	AMG-479	Phase 3 Clinical	Amgen Inc	Sarcoma, Ewing; Neoplasm Metastasis; Neuroectodermal Tumors, Primitive, Peripheral; Carcinoma, Non-Small-Cell Lung; Lymphoma; Lung Neoplasms; Rhabdomyosarcoma, Alveolar; Colorectal Neoplasms; Neuroectodermal Tumors, Primitive; Prostatic Neoplasms; Breast Neoplasms; Solid tumours; Sarcoma; Pancreatic Neoplasms; Small Cell Lung Carcinoma; Neoplasms; Carcinoid Tumor; Rhabdomyosarcoma, Embryonal; Ovarian Neoplasms; Intestinal Neoplasms; Bone metastases; Rhabdomyosarcoma	Details
Linsitinib	OSI-906; ASP-7487; OSI-906AA	Phase 3 Clinical	Astellas Pharma Inc, National Cancer Institute	Multiple Myeloma; Paraganglioma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Orbital Diseases; Eye Diseases; Colorectal Neoplasms; Gastrointestinal Stromal Tumors; Exophthalmos; Breast Neoplasms; Prostatic Neoplasms; Sarcoma, Ewing; Adrenocortical Carcinoma; Thyroid Diseases; Graves Ophthalmopathy; Endocrine System Diseases; Skin Neoplasms; Neoplasms; Small Cell Lung Carcinoma; Pancreatic Neoplasms; Hashimoto Disease; Head and Neck Neoplasms; Ovarian Neoplasms; Carney Complex; Liver Neoplasms; Solid tumours; Chondrosarcoma	Details
Conteltinib	CT-707; SY-707	Phase 3 Clinical		Pancreatic Neoplasms; Carcinoma, Non-Small-Cell Lung	Details
FPI-1434	[225Ac]-FPI-1434; FPX-01	Phase 2 Clinical	Fusion Pharma	Ovarian Neoplasms; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms; Neoplasms; Adrenocortical Carcinoma; Uveal melanoma; Breast Neoplasms; Endometrial Neoplasms; Uterine Cervical Neoplasms	Details
Dalotuzumab	h7C-10; MK-0646; F-50-035	Phase 2 Clinical	Pierre Fabre Group	Solid tumours; Rectal Neoplasms; Pancreatic Neoplasms; Small Cell Lung Carcinoma; Neoplasms; Neuroendocrine Tumors; Multiple Myeloma; Breast Neoplasms; Colorectal Neoplasms; Lung Neoplasms; Carcinoma, Neuroendocrine; Carcinoma, Non-Small-Cell Lung	Details
CT-102	CT-102	Phase 2 Clinical	Hangzhou Tianlong Pharmaceutical Co Ltd, Institute Of Radiation And Radiation Medicine, Chinese Academy Of Military Medical Sciences	Liver Neoplasms; Carcinoma, Hepatocellular	Details
Mecasermin Rinfabate	OHB-607; SHP-607; HGT-ROP-001; rhIGF-I/rhIGFBP-3; TAK-607	Phase 2 Clinical	Insmed	Noonan Syndrome; Failure to Thrive; Cerebral Intraventricular Hemorrhage; Bronchopulmonary Dysplasia; Myotonic Dystrophy; Retinopathy of Prematurity; Muscular Dystrophies; Laron Syndrome	Details
Insulin growth factor receptor type 1 antisense therapy (Imvax)	IGV-001	Phase 2 Clinical	Thomas Jefferson University	Glioblastoma	Details
MHB018A		Phase 2 Clinical	Minghui Pharmaceutical (Hangzhou) Co Ltd	Graves Ophthalmopathy	Details
Lonigutamab	VB-421	Phase 2 Clinical	Pierre Fabre Group	Graves Ophthalmopathy	Details
Cixutumumab	A-12; IMC-A12; LY-3012217; NSC-742460	Phase 2 Clinical	Eli Lilly And Company	Gastrinoma; Adenocarcinoma, Bronchiolo-Alveolar; Gliosarcoma; Colorectal Neoplasms; Neuroblastoma; Medullary thyroid cancer (MTC); Chondrosarcoma, Extraskeletal Myxoid; Retinoblastoma; Neurofibrosarcoma; Brain Stem Neoplasms; Lymphoma, Mantle-Cell; Breast Neoplasms; Osteosarcoma; Prostatic Neoplasms; Sarcoma; Sarcoma, Ewing; Liposarcoma; Esophageal adenocarcinoma; Neuroectodermal Tumors, Primitive, Peripheral; Adenocarcinoma; Melanoma; Paraganglioma; Breast Neoplasms, Male; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Sarcoma, Alveolar Soft Part; Adrenocortical Carcinoma; Rhabdomyosarcoma, Alveolar; Carcinoma, Neuroendocrine; Glioma; Esophageal Squamous Cell Carcinoma; Hemangiopericytoma; Lung Neoplasms; Pinealoma; Rectal Neoplasms; Carcinoma, Merkel Cell; Stomach Neoplasms; Hemangiosarcoma; Insulinoma; Hepatoblastoma; Esophageal Neoplasms; Mesenchymoma; Squamous Cell Carcinoma of Head and Neck; Rhabdomyosarcoma, Embryonal; Carcinoma; Fibrosarcoma; Kidney Neoplasms; Liver Neoplasms; Head and Nec	Details
Picropodophyllin	PPP; AXL-1717; NSC-36407	Phase 2 Clinical	Axelar Ab	Astrocytoma; Carcinoma, Non-Small-Cell Lung	Details
NNC0268-0965	NNC0268-0965	Phase 1 Clinical	Novo Nordisk A/S	Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2	Details
IGF-1 receptor oligodeoxynucleotide-based immunotherapy (Thomas Jefferson University)		Phase 1 Clinical	Sidney Kimmel Cancer Center	Glioma	Details
Insulin-Like Growth Factor 1 (Wright State Physicians)		Phase 1 Clinical	Wright State Physicians	Nasolabial fold wrinkles; Burns; Sunburn	Details
SAR-446159	ABL-301; SAR-446159	Phase 1 Clinical	Abl Bio Inc	Parkinson Disease	Details
VRDN-003	VRDN-003	Phase 1 Clinical	Viridian Therapeutics Inc	Graves Ophthalmopathy	Details
VRDN-002	VRDN-002	Phase 1 Clinical	Viridian Therapeutics Inc	Graves Ophthalmopathy	Details
LX-101 (Lirum Therapeutics)	765IGF-MTX; IGF/MTX	Phase 1 Clinical	Lirum Therapeutics Inc	Head and Neck Neoplasms; Anemia, Refractory, with Excess of Blasts; Myelodysplastic Syndromes; Leukemia, Myelomonocytic, Chronic; Neoplasms; Graves Ophthalmopathy; Breast Neoplasms; Brain Neoplasms; Genital Neoplasms, Female; Urogenital Neoplasms; Melanoma; Gastrointestinal Neoplasms	Details
ZB-011	ZB-011; ZB011	Phase 1 Clinical	Viridian Therapeutics Inc	Graves Ophthalmopathy	Details
Teprotumumab(Zhejiang Boxiao Bio-pharma)		Phase 1 Clinical	Zhejiang Boxiao Bio-pharmaceutical Co Ltd	Graves Ophthalmopathy	Details
PHP-1003	PHP-1003; PHP1003	Phase 1 Clinical	Suzhou Pulekang Pharmaceutical Technology Co Ltd	Graves Ophthalmopathy	Details
124I-CPD-1023-figitumumab	124I-CPD-1028; 125I-CPD-1028; CPD-1028-[124I]; CPD-1028-[125I]; FPX-1028	Phase 1 Clinical	Fusion Pharma	Neoplasms	Details

Inverkehr gebrachte Arzneimittelinformation

Englischer Name	Forschungscode	Forschungsphase	Firma	Frühestes Markenname	Frühestes Genehmigungsland	Früheste Indikation	Früheste Genehmigungsgesellschaft	Früheste Genehmigungsdatum	Indikationen	Klinische Studie
Mecasermin (Astellas/OrphanPacific)		Approved	Astellas Pharma Inc	Somazon	Japan	Growth hormone deficiency; Diabetes Mellitus, Lipoatrophic; Dwarfism	null	1994-10-05	Diabetes Mellitus, Lipoatrophic; Heart Failure; Myocardial Infarction; Multiple Sclerosis; HIV-Associated Lipodystrophy Syndrome; Dwarfism; Growth hormone deficiency	Details
Mecasermin (Ipsen)	IGF-1; FK-780; MKN-031	Approved	Ipsen	Increlex	United States	Failure to Thrive	Ipsen Inc	2005-08-30	Failure to Thrive; Autism Spectrum Disorder; X-Linked Combined Immunodeficiency Diseases; Phelan-McDermid syndrome; Growth Disorders; Muscular Dystrophy, Duchenne; Laron Syndrome	Details
Brigatinib	AP-26113	Approved	Ariad Pharmaceuticals Inc	Alunbrig, ALUNBRIG	United States	Carcinoma, Non-Small-Cell Lung	Takeda Pharmaceuticals USA Inc	2017-04-28	Solid tumours; Ependymoma; Carcinoma; Neoplasms; Neurofibromatosis 2; Myofibroma; Lymphoma, Large-Cell, Anaplastic; Granuloma, Plasma Cell; Lung Neoplasms; Brain metastases; Carcinoma, Non-Small-Cell Lung; Sarcoma, Kaposi; Neurilemmoma; Neuroma, Acoustic; Meningioma	Details
IGF-1 (Biogen/Pharmacia & Upjohn)		Approved	Biogen Inc, Pharmacia & Upjohn	Igef	Sweden	Dwarfism	null	1994-01-01	Dwarfism	Details
Ceritinib	LDK-378; NVP-LDK378; NVP-LDK378-NX	Approved	Novartis Pharma Ag	赞可达, Zykadia	EU	Carcinoma, Non-Small-Cell Lung	Novartis Europharm Ltd	2014-04-29	Hepatic Insufficiency; Adenocarcinoma; Melanoma; Carcinoma, Non-Small-Cell Lung; Brain metastases; Esophageal adenocarcinoma; Granuloma, Plasma Cell; Lymphoma, Large-Cell, Anaplastic; Thyroid Neoplasms; Hematologic Neoplasms; Colorectal Neoplasms; Cholangiocarcinoma; Neoplasms; Pancreatic Neoplasms; Glioblastoma; Thyroid Carcinoma, Anaplastic; Stomach Neoplasms	Details
Teprotumumab	R-1507; RG-1507; RO-4858696; HZN-001; RV-001（River Vision）	Approved	Genmab A/S, F. Hoffmann-La Roche Ltd	Tepezza	United States	Graves Ophthalmopathy	Horizon Therapeutics Ireland	2020-01-21	Neoplasms; Graves Ophthalmopathy; Sarcoma; Breast Neoplasms; Diabetic macular oedema; Scleroderma, Diffuse; Carcinoma, Non-Small-Cell Lung	Details