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high-throughput solutions for vaccine R&D based on ELISA

Vaccination is one of the most important and economic tools to protect the community from infectious diseases. There are about 60% of the population were fully vaccinated around the world, however, as the virus mutates continuously, the increasingly strong transmission and immune escape capabilities of the mutant strains have brought great challenges to the prevention and control of the epidemic. The emergence of many breakthrough infection cases represents that the "immune barrier" created by vaccination against the wild-type strain of COVID-19 may be flawed. Therefore we urgently need next-generation vaccines that still have high protective efficacy against mutant strains.
As the world experiences a new wave of outbreaks due to the emergence of the Omicron variant, vaccine manufacturers have already stepped up for the development of vaccines against new variants. Earlier, Moderna and Pfizer had announced to start the research on candidate vaccines against Delta and Omicron variants.
ACROBiosystems has undergone methodological validation and independently developed a series of COVID-19-related ELISA kits according to the application as described in the guidelines, aiming to provide comprehensive solutions ranging from quality control of vaccine production to preclinical and clinical research.
Advantages:
- For wild type and VOCs (Alpha, Beta, Gamma, Delta, Omicron) detection;
- Can detect antigens and antibodies (including neutralizing antibodies, total antibodies, IgG, IgM, IgG antibody subtypes, etc.);
- Cover species of Human, Mouse and Monkey, to meet the needs of preclinical and clinical research;
- Strict quality control to ensure that the batch-to-batch difference and precision <10%;
- High throughput, can detect 90+ samples within 2 hours;
- Low environmental requirements, simple operation.

Manufacture and quality control——Antigen detection

Antigen detection
Product list:
Cat. No. Product Description Preorder/Order
RAS-A117 SARS-CoV-2 Spike RBD (BA.4 & BA.5) ELISA Kit

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RAS-A149 SARS-CoV-2 Spike Trimer (XBB.1) ELISA Kit (For Vaccine Development)

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RAS-A145 SARS-CoV-2 Spike Trimer (XBB.1.5) ELISA Kit (For Vaccine Development)

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Preclinical research——Immunogenicity assay

Immunogenicity assay
Product list:
Cat. No. Coated Antigen Product Description Preorder/Order
RAS-T142 Spike RBD Mouse Anti-SARS-CoV-2 (XBB.1.5) Antibody IgG Titer Serologic Assay Kit (Spike RBD)

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RAS-T045 Spike S1 Mouse Anti-SARS-CoV-2 Antibody IgG Titer Serologic Assay Kit (Spike S1)

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Assay Data:

Cat. No. RAS-T045 can be used to detect the mouse IgG antibody titer, the titer value is 12800.

Clinical research——Serum immune detection

IgG Antibody Titer Detection
Product list:
Cat. No. Coated Antigen Product Description Preorder/Order
RAS-T139 Spike RBD Human Anti-SARS-CoV-2 (XBB.1.5) Antibody IgG Titer Serologic Assay Kit (Spike RBD)

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RAS-T110 Spike Trimer Human Anti-SARS-CoV-2 (BA.2.12.1) Antibody IgG Titer Serologic Assay Kit (Spike Trimer)

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RAS-T095 Spike RBD Human Anti-SARS-CoV-2 (BA.4 & BA.5) Antibody IgG Titer Serologic Assay Kit (Spike RBD)

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RAS-T074 Spike RBD Human Anti-SARS-CoV-2 (B.1.1.529) Antibody IgG Titer Serologic Assay Kit (Spike RBD)

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RAS-T075 Spike Trimer Human Anti-SARS-CoV-2 (B.1.1.529) Antibody IgG Titer Serologic Assay Kit (Spike Trimer)

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>>> Click to find out more ELISA kits for IgM/ Total antibody detection

ADE/VED study
Product list:
COVID-19 Variant Cat. No. Product Description Preorder/Order
Wild type RAS-T015 Anti-SARS-CoV-2 Antibody IgG2 Titer Serologic Assay Kit

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Wild type RAS-T017 Anti-SARS-CoV-2 Antibody IgG4 Titer Serologic Assay Kit

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  • Background
  • Manufacture and quality control——Antigen detection
  • Preclinical research——Immunogenicity assay
  • Clinical research——Serum immune detection
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