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This product is in development. If you are interested in this product, please contact us directly. We will accelerate our R&D process according to your needs and reserve the product for you.
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E2P-C52H7-100ug
$300.00
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E2P-C52H7-1mg
$1,980.00
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E2P-C52H7
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  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources

分子别名（Synonym）

E2

表达区间及表达系统（Source）

Hepacivirus C E2, His Tag (E2P-C52H7) is expressed from human 293 cells (HEK293). It contains AA Ala 1 - Cys 190 (Accession # Q0N1H1-1).

Predicted N-terminus: Ala 1

蛋白结构（Molecular Characterization）

Online-Res(Ala 1 - Cys 190) Q0N1H1-1

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 22.6 kDa.

内毒素（Endotoxin）

制剂（Formulation）

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. -20°C to -70°C for 12 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.

Background

Glycoprotein E2 is an approximately 50 kDa viral envelope protein encoded by the hepatitis C virus (HCV) genome. HCV infection often progresses to severe, liver-associated diseases, such as cirrhosis, steatosis, and hepatocellular carcinoma. Both E1 and E2 are essential for infectivity, with E2 possessing the binding sites for the entry receptors CD81 and SCARB1.Moreover, glycoprotein E2 is BDCA-2 ligand and acts as an inhibitor of IFN production by plasmacytoid dendritic cells.