Influenza A virus (Darwin/6/2021) & (Darwin/9/2021) NP (H3N2) Protein, His Tag

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NP2-V52H3-100ug
$350.00
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NP2-V52H3-1mg
$2,680.00
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NP2-V52H3
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Synonyms

Nucleocapsid protein/NP (Influenza Virus)

Source

Influenza A virus (Darwin/6/2021) & (Darwin/9/2021) NP (H3N2) Protein, His Tag (NP2-V52H3) is expressed from Baculovirus-Insect cells. It contains AA Met 1 - Asn 498 (Accession # EPI1884976, GISAID).

Predicted N-terminus: Met 1

Molecular Characterization

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 57.8 kDa. The protein migrates as 55-64 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Endotoxin

Less than 1.0 EU per μg by the LAL method / rFC method.

Purity

>90% as determined by SDS-PAGE.

Formulation

Supplied as 0.2 μm filtered solution in 50 mM Tris, 500 mM NaCl, pH7.5 with glycerol as protectant.

Contact us for customized product form or formulation.

Shipping and Storage

This product is supplied and shipped on dry ice.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • The product MUST be stored at -70°C or lower upon receipt;
  • -70°C for 3 months under sterile conditions.

Background

Influenza, commonly known as ‘the flu’, is an infectious disease of birds and mammals caused by RNA viruses of the family Orthomyxoviridae, the influenza viruses.Influenza viral nucleoprotein (NP) is highly conserved and the most abundant non-enzymatic viral protein in infected cells. NP is a key component of the viral ribonucleoproteins (vRNPs) complex, and its recognized functions include, but are not limited to, binding to RNA and oligomerizing for the vRNP complex, undergoing intracellular trafficking, and participating in the switch from mRNA transcription to vRNA replication.