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PE-Labeled Human HLA-A*33:03&B2M&EGF R (HVKITDFGR) Tetramer Protein

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HLR-HP2H3-25ug
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Product Details
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  • Product Details
  • Performance Data
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  • Important Statement
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Synonyms

HLA-A*3303 & B2M & EGF R (HVKITDFGR)

Source

PE-Labeled Human HLA-A*33:03&B2M&EGF R (HVKITDFGR) Tetramer Protein (HLR-HP2H3) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Ile 308 (HLA-A*33:03) & Ile 21 - Met 119 (B2M) & HVKITDFGR peptide (Accession # AAA79865.1 (HLA-A*33:03) & P61769-1 (B2M) & HVKITDFGR).

Predicted N-terminus: Gly 25 & His

Molecular Characterization

PE-Labeled Human HLA-A*33:03&B2M&EGF R (HVKITDFGR) Tetramer Protein is assembled by biotinylated monomer and streptavidin.

Biotinylated Human HLA-A*33:03&B2M&EGF R (HVKITDFGR) Complex Protein is produced by co-expression of HLA-A*33:03 and B2M loaded with EGF R peptide. Biotinylated Human HLA-A*33:03&B2M&EGF R (HVKITDFGR) Complex Protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).

Conjugate

PE

Excitation Wavelength: 488 nm / 561 nm

Emission Wavelength: 575 nm

Formulation

Lyophilized from 0.22 μm filtered solution in PBS, 1% BSA, 50-150 mM NaCl with trehalose as protectant.

Contact us for customized product form or formulation.

Reconstitution

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

Shipping and Storage

This product is shipped at ambient temperature.

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please protect from light and avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • -20°C to -70°C for 12 months in lyophilized state;
  • -70°C for 3 months under sterile conditions after reconstitution.
ACRO Quality Management System

Background

The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer. The Human HLA-A*3303 & B2M & EGF R(HVKITDFGR) protein is a complex of HLA-A*3303 of the MHC Class I, B2M, and HVKITDFGR peptide of the EGF R.