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Human ANGPTL7 / CDT6 Protein, His Tag (MALS verified)

AIDD‑Ready
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AN7-H52H3-100ug
$420.00
In Stock - Delivery in 2-3 weeks
AN7-H52H3-1mg
$3,060.00
In Stock - Delivery in 1-2 business days
AN7-H52H3
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Product Details
Performance Data
Reviews & Citations
Resources
  • Product Details
  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources
Synonyms

ANGPTL7, CDT6

Source

Human ANGPTL7 Protein, His Tag (AN7-H52H3) is expressed from human 293 cells (HEK293). It contains AA Gln 27 - Pro 346 (Accession # O43827-1).

Molecular Characterization
Other Tags and Version Biotin & Other Labeled Version

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 39.0 kDa. The protein migrates as 48-55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

The protein is designed as a trimer.

Endotoxin

Less than 1.0 EU per μg by the LAL method / rFC method.

Purity

>90% as determined by SDS-PAGE.

>90% as determined by SEC-MALS.

Formulation

Supplied as 0.2 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

Shipping and Storage

This product is supplied and shipped on dry ice.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • The product MUST be stored at -70°C or lower upon receipt;
  • -70°C for 3 months under sterile conditions.
ACRO Quality Management System

Background

Angiopoietin-like 7 (ANGPTL7), also known as cornea-derived transcript 6 (CDT6), is a secreted glycoprotein structurally related to the angiopoietins. It is expressed in the corneal stroma, trabecular meshwork, and sclera, and is elevated in the aqueous humor of glaucoma patients. Recently, ANGPTL proteins, including ANGPTL-2, -3, -5, and -7, have been identified as factors that, in combination with SCF, thrombopoietin (TPO), IGF-II, and acidic FGF (FGF-1), enhance the expansion and engraftment of human and mouse hematopoietic stem cells.