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Human Adiponectin Protein, premium grade

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ADQ-H5218-100ug
$205.00
In Stock - Delivery in 1-2 business days
ADQ-H5218-1mg (500ug X 2)
$1,730.00
In Stock - Delivery in 2 weeks
ADQ-H5218
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Product Details
Performance Data
Reviews & Citations
Resources
  • Product Details
  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources
Synonyms

ADIPOQ, Adiponectin, ACDC, ACRP30, APM1, GBP28

Source

Human Adiponectin Protein, premium grade (ADQ-H5218) is expressed from human 293 cells (HEK293). It contains AA Lys 101 - Asn 244 (Accession # Q15848-1).

Predicted N-terminus: Lys 101

It is produced under our rigorous quality control system that incorporates a comprehensive set of tests including sterility and endotoxin tests. Product performance is carefully validated and tested for compatibility for cell culture use or any other applications in the early preclinical stage. When ready to transition into later clinical phases, we also offer a custom GMP protein service that tailors to your needs. We will work with you to customize and develop a GMP-grade product in accordance with your requests that also meets the requirements for raw and ancillary materials use in cell manufacturing of cell-based therapies.

Molecular Characterization
Other Tags and Version Biotin & Other Labeled Version

This protein carries no "tag".

The protein has a calculated MW of 16.6 kDa. The protein migrates as 16 kDa±3 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

Endotoxin

Less than 0.01 EU per μg by the LAL method / rFC method.

Host Cell DNA

<0.02 ng/μg of protein tested by qPCR.

Sterility

Negative

Mycoplasma

Negative

Purity

>95% as determined by SDS-PAGE.

>90% as determined by SEC-MALS.

Formulation

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

Reconstitution

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

Shipping and Storage

This product is shipped at ambient temperature.

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • -20°C to -70°C for 12 months in lyophilized state;
  • -70°C for 3 months under sterile conditions after reconstitution.
ACRO Quality Management System

Background

Adiponectin is a cytokine that is secreted from adipose tissues (adipokine), which consists of a 60 amino acid (aa) N‑terminal collagenous region and a 137 aa C‑terminal C1q-like globular domain which can be cleaved by a leukocyte-derived elastase. Adiponectin is involved in a variety of physiological functions, molecular and cellular events, including lipid metabolism, energy regulation, immune response and inflammation, and insulin sensitivity and is negatively correlated with obesity, type 2 diabetes, and atherogenesis. It also has a protective effect on neurons and neural stem cells. Adiponectin can be found in three forms with different molecular weights, namely, a low molecular weight (LMW), a moderate molecular weight (MMW), and a high molecular weight (HMW) form. The various multimeric forms of Adiponectin exhibit distinct tissue specific and gender specific profiles and activities.