Monoclonal Anti-Glycoprotein H & Glycoprotein L/gH & gL (EBV) Antibody, Human IgG1 (8C5)

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GHL-MY2403-100ug
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Source

Monoclonal Anti-Glycoprotein H & Glycoprotein L/gH & gL (EBV) Antibody, Human IgG1 (8C5) is recombinantly expressed in HEK293. It consists of mouse variable regions genetically fused to human constant domains.

Antibody Type

Recombinant Monoclonal

Clone

8C5

Isotype

Human IgG1, Kappa

Host Species

Mouse

Reactivity

Virus

Immunogen

Recombinant Epstein-Barr virus Glycoprotein H&Glycoprotein L Heterodimer Protein is expressed from human 293 cells

Specificity

Specifically recognizes Epstein-Barr virus Glycoprotein H&Glycoprotein L Heterodimer Protein.

Application
Application
Recommended Use
Western Blot
0.5-0.02 μg/mL
ELISA
0.2-2 μg/mL

* Recommended dilutions are for reference only. Optimal working concentrations may vary depending on your consumables, reagents, and assay conditions. We recommend optimizing for your specific system. No warranty is made regarding performance at any specific dilution.

Purification

Protein A purified.

Aggregation

Less than 5%, as determined by SEC-MALS.

Concentration

Please refer to the Certificate of Analysis (CoA).

Form

Lyophilized

Formulation

Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

Please contact us for customized product forms or formulations.

Reconstitution

Please refer to the Certificate of Analysis (CoA) for specific instructions.

Shipping

Lyophilized product is shipped at ambient temperature.

Storage

For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • -20°C to -70°C for 12 months in lyophilized state;
  • -70°C for 3 months under sterile conditions after reconstitution.
Notices

Product Specific Notices: For research use only.

Background Introduction

The Epstein–Barr virus (EBV) glycoproteins H (gH) and L (gL) form a heterodimer essential for viral entry into host cells. This complex mediates membrane fusion in cooperation with other viral glycoproteins, enabling EBV to infect both B lymphocytes and epithelial cells. Antibodies targeting gH/gL can block this fusion process, thereby neutralizing infection. Such antibodies are valuable tools for studying EBV pathogenesis, evaluating vaccine candidates, and developing diagnostic assays. Because gH/gL are conserved and exposed on the viral envelope, they elicit strong immune responses, making anti‑gH/gL antibodies important in both research and potential therapeutic applications.