Monoamine oxidase B Molekülinformation
Molecule Name
Monoamine oxidase B
Molekülalias
MAOB, MAO-B,Monoamine Oxidase B,Monoamine oxidase type B
Drug Development Progress
Anzahl der klinischen Arzneimittel13
Anzahl der inverkehr gebrachten Arzneimittel3
Höchste Forschungs- und EntwicklungsphaseApproved
Target-Alias
EC:1.4.3.4，EC 1.4.3，MAOB，Amine oxidase [flavin-containing] B，Monoamine Oxidase B，Monoamine Oxidase Type B，MAO-B，Adrenalin Oxidase，Tyramine Oxidase，MAO， Platelet，MAO， Brain，EC 1.4.3.4
Molekülhintergrund
Monoamine Oxidase Type B (MAOB) is an enzyme located in the outer mitochondrial membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the breakdown of dopamine in the brain. MAOB inhibitors, that reduces dopamine turnover, are in clinical use for the treatment of Parkinson's disease (PD).
Monoamine oxidase B Produktliste
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Lizenzierungszusammenarbeit
| Projektname | Arzneimitteltyp | Therapiegebiet | Indikationen | Stufe | Rechtsgebiet |
|---|---|---|---|---|---|
| Reversible MAOB Inhibitor | Small molecule | Neurological disease | Parkinson's disease | Phase I | Global |
- Projektname
- Reversible MAOB Inhibitor
- Arzneimitteltyp
- Small molecule
- Therapiegebiet
- Neurological disease
- Indikationen
- Parkinson's disease
- Stufe
- Phase I
- Rechtsgebiet
- Global