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MIS RII

MIS RII Overview

English Name	Anti-Mullerian hormone receptor II	Approved Drugs	0
Drugs in Clinical Trials	0	Target Synonym	Anti-Mullerian Hormone Receptor， Type II，AMHR2，MRII，AMH Type II Receptor，MISRII，Muellerian Inhibiting Substance Type II Receptor，MIS Type II Receptor，Anti-Muellerian hormone type-2 receptor，EC:2.7.11.30，Mullerian Inhibiting Substance Type II Receptor，MISR2，AMHR，Anti-Muellerian Hormone Type-2 Receptor，Anti-Mullerian Hormone Receptor Type 2，EC 2.7.11.30，Anti-Muellerian Hormone Type II Receptor，Anti-Mullerian Hormone Receptor Type II
Highest Development Stage	Preclinical

English Name	Anti-Mullerian hormone receptor II
Target Synonym	Anti-Mullerian Hormone Receptor， Type II，AMHR2，MRII，AMH Type II Receptor，MISRII，Muellerian Inhibiting Substance Type II Receptor，MIS Type II Receptor，Anti-Muellerian hormone type-2 receptor，EC:2.7.11.30，Mullerian Inhibiting Substance Type II Receptor，MISR2，AMHR，Anti-Muellerian Hormone Type-2 Receptor，Anti-Mullerian Hormone Receptor Type 2，EC 2.7.11.30，Anti-Muellerian Hormone Type II Receptor，Anti-Mullerian Hormone Receptor Type II
Approved Drugs	0
Drugs in Clinical Trials	0
Highest Development Stage	Preclinical

MIS RII Product List

Product Category
Protein (7)
Product Status
Launched (7)
Species
Human (5)Cynomolgus (1)Mouse (1)
Tag
Fc Tag (1)His Tag (3)His Tag & Avi Tag (1)Mouse IgG Fc Tag (1)Llama IgG Fc Tag (1)
Conjugate
Unconjugated (6)Biotin-labeled (1)

Cat. No.	Species	Host	Product Description
HOT MII-H5253	Human	HEK293	Human MIS RII Protein, Mouse IgG2a Fc Tag
HOT MII-H5258	Human	HEK293	Human MIS RII Protein, Fc Tag
HOT MII-H52H6	Human	HEK293	Human MIS RII Protein, His Tag
HOT MII-M52H6	Mouse	HEK293	Mouse MIS RII Protein, His Tag
MII-H5254	Human	HEK293	Human MIS RII Protein, Llama IgG2b Fc Tag, low endotoxin
MII-H82E3	Human	HEK293	Biotinylated Human MIS RII Protein, His,Avitag™
MII-C52H5	Cynomolgus	HEK293	Cynomolgus MIS RII Protein, His Tag

Total: 7

MIS RII Background

MIS RII (Mullerian inhibiting substance type II receptor), also known as AMHRII (anti-Mullerian hormone type II receptor), is a serine/threonine receptor with a single transmembrane domain that belongs to the family of type II receptors of the TGF-beta superfamily. Mutations in MIS RII result in persistent Mullerian duct syndrome (PMDS), persistent Müllerian duct syndrome (PMDS) is a sex-limited disorder in which males develop portions of the female reproductive tract. Anti-Müllerian hormone (AMH) and its receptor (AMHR2) induce the regression of the Müllerian ducts in male embryos, but the mechanism by which the Amhr2 gene is specifically activated is not fully understood.

MIS RII Synonyms

MIS RII,MRII,AMHR2,AMHR,MISR2,AMH type II receptor

Product Reviews

K***n2025-04-29
0People Like
Human MIS RII Protein, Fc Tag
We purchased this protein and validated its binding to its natural ligand, MIS. We saw great binding between the hMISRII-hFc and MIS ligand, which was exactly what we expected. Additionally, this protein passed our QC requirements for purity on SDS-PAGE and SEC. This was purchased along with several other MISRII products from other companies and this was the only material that bound MIS with expected affinity. As such, we plan to use this protein for our downstream applications.