Erythropoietin R Molekülinformation
Molecule Name
Erythropoietin receptor
Molekülalias
EPOR
Drug Development Progress
Anzahl der klinischen Arzneimittel34
Anzahl der inverkehr gebrachten Arzneimittel83
Höchste Forschungs- und EntwicklungsphaseApproved
Target-Alias
EPOR，Erythropoietin Receptor，EPO-R，Receptors， Erythropoietin，Truncated Erythropoietin Receptor
Molekülhintergrund
Erythropoietin (EPO) is the major glycoprotein hormone regulator of mammalian erythropoiesis , and is produced by kidney and liver in an oxygen-dependent manner. The biological effects of EPO are mediated by the specific erythropoietin receptor (EPOR) on bone marrow erythroblasts, which transmits signals important for both proliferation and differentiation along the erythroid lineage. EPOR is a type 1 single-transmembrane cytokine receptor, and belongs to the homodimerizing subclass which functions as ligand-induced or ligand-stabilized homodimers. EPOR pre-exists as dimers which upon binding of a 34 kDa ligand erythropoietin (Epo), changes its homodimerized state. These conformational changes result in the autophosphorylation of Jak2 kinases that are pre-associated with the receptor. Erythropoietin is necessary to maintain endothelial cells and to promote tumor angiogenesis, hence the dysregulation of EpoR may affect the growth of certain tumors. EpoR signaling prevents neuronal death and ischemic injury.
Erythropoietin R Produktliste
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Klinische Arzneimittelinformation
| Englischer Name | Forschungscode | Forschungsphase | Firma | Indikationen | Klinische Studie |
|---|---|---|---|---|---|
| Pegylated darbepoetin beta | BCD-131 | Phase 3 Clinical | BIOCAD JSC | Anemia; Renal Insufficiency, Chronic | Details |
| Epoetin alfa biosimilar (Apotex) | APO-EPO | Phase 3 Clinical | Apotex | Anemia | Details |
| Epoetin alfa biosimilar (UBI Pharma) | UB-851 | Phase 3 Clinical | United Biomedical Inc | Anemia | Details |
| Epoetin alfa biosimilar (PanGen Biotech) | PDA-10 | Phase 3 Clinical | Pangen Biotech | Anemia | Details |
| Epoetin alfa biosimilar (Megalabs) | Phase 3 Clinical | Megalabs | Anemia | Details | |
| Darbepoetin alfa biosimilar (Reliance Life Sciences) | RTPR-026; R-TPR-026 | Phase 3 Clinical | Reliance Life Sciences | Anemia | Details |
| Erythropoietin Hydrogel(Ain Shams University) | Phase 3 Clinical | Ain Shams University | Lichen Planus, Oral | Details | |
| Darbepoetin alfa biosimilar (Hallym University Medical Center) | Phase 3 Clinical | Hallym University Medical Center | Anemia | Details | |
| Recombinant human erythropoietin(Asociación para Evitar la Ceguera en México) | Phase 3 Clinical | Asociación Para Evitar La Ceguera En México | Toxic Optic Neuropathy | Details | |
| Erythropoietin polysialic (Xenetic Biosciences) | PSA-EPO; SYN-20070131RU | Phase 3 Clinical | Lipoxen Technologies Ltd, Serum Institute Of India Ltd | Anemia | Details |
| Darbepoetin alfa biosimilar (Nanogen) | Phase 3 Clinical | Nanogen Pharmaceutical Biotechnology Joint Stock Company | Anemia; Renal Insufficiency, Chronic | Details | |
| Erythropoietin (Neose) | NE-180 | Phase 2 Clinical | Neose Technologies | Anemia | Details |
| Erythropoietin biosimilar (Pooyesh Darou) | Phase 2 Clinical | Pooyesh Darou | Anemia | Details | |
| Erythropoietin (Y-shaped pegylation, Xiamen Amoytop Biotech) | YPEG-EPO; YPEG-rhEPO | Phase 2 Clinical | Biogeneric Pharma, Xiamen Amoytop Biotech Co Ltd | Anemia; Growth Disorders; Growth hormone deficiency; Idiopathic short stature; Renal Insufficiency | Details |
| Recombinant human erythropoietin-Fc fusion protein (Dongguan baolijian Biotech) | Phase 2 Clinical | Dongguan Baolijian Bioengineering Research And Development Co Ltd, Dongguan Taili Biological Engineering Co Ltd | Anemia | Details | |
| Darbepoetin alfa biosimilar (CJ Healthcare) | YLB-217; CJ-40001 | Phase 2 Clinical | Cj Cheiljedang Corp | Anemia | Details |
| LKA-651 | LKA-651; LKA651; NOV-9 | Phase 2 Clinical | Alcon, Morphosys Ag | Diabetic macular oedema; Macular Degeneration; Macular Edema; Retinal Vein Occlusion | Details |
| Pegylated recombinant human erythropoietin (Shenzen Saibaoer Biotech) | Phase 2 Clinical | Shenzhen Sciprogen Bio-Pharmaceutical Co Ltd | Anemia | Details | |
| ADCC-R-Epo-R T-cells therapy(National University Hospital) | Phase 2 Clinical | National University Hospital (Singapore) | Breast Neoplasms; Solid tumours | Details | |
| Recombinant Peglated human erythropoietin（Angde ） | Phase 2 Clinical | China Resources Angde Biotech Pharma Co Ltd | Anemia | Details | |
| Recombinant human erythropoietin (Hanyang University Seoul Hospital) | Phase 2 Clinical | Hanyang University, Hanyang University Seoul Hospital | Amyotrophic Lateral Sclerosis | Details | |
| Recombinant human erythropoietin-CTP fusion protein (Harbin Pharmaceutical) | Phase 1 Clinical | Harbin Pharmaceutical Group Holding Co Ltd | Anemia | Details | |
| rhEPO-Fc (Shanghai Meiye Biotechnology) | Phase 1 Clinical | Shanghai Meiye Biotechnology Co Ltd | Anemia | Details | |
| Recombinant erythropoietin (Prolong Pharmaceuticals/Zydus Cadila) | ZY-7318 | Phase 1 Clinical | Prolong Pharmaceuticals Llc, Zydus Cadila | Anemia; beta-Thalassemia | Details |
| Erythropoietin receptor agonist (Biocad) | Phase 1 Clinical | BIOCAD JSC, Ligand Pharmaceuticals Inc | Hematologic Diseases | Details | |
| Albumin-erythropoietin fusion protein (Tianjin SinoBiotech) | Phase 1 Clinical | Tianjin Puying Biotechnology Co Ltd | Anemia | Details | |
| SFR-1882 | SFR-1882 | Phase 1 Clinical | Tianjin Sinobiotech Ltd | Anemia; Renal Insufficiency | Details |
| Novel erythropoiesis stimulant (Centergene) | Phase 1 Clinical | Shanghai Qiangbang Biological Technology Co Ltd, Suzhou Kangju Biotechnology Co Ltd, Suzhou Shengji Pharmaceutical Co Ltd | Anemia | Details | |
| Darbepoetin biosimilar (Hetero Biopharma) | Phase 1 Clinical | Hetero Biopharma Ltd | Details | ||
| long-acting EPO (UBI Pharma) | UB-852 | Phase 1 Clinical | Ubi Pharma | Anemia | Details |
| JL-14001 | JL-14001; JL14001 | Phase 1 Clinical | Jieku (Shanghai) Biomedical Research Co Ltd | Anemia; Renal Insufficiency, Chronic | Details |
| LP-001 | LP-001 | Phase 1 Clinical | Longbio Pharma (Suzhou) Co Ltd | Anemia, Myelophthisic; Hematologic Neoplasms; Myelodysplastic Syndromes | Details |
| Recombinant erythropoietin (University of Chile) | Clinical | University Of Chile | Anemia; Renal Insufficiency, Chronic | Details | |
| Darbepoetin alfa biosimilar (PanPharmaceuticals) | Clinical | Panpharmaceuticals | Anemia | Details |
Inverkehr gebrachte Arzneimittelinformation
| Englischer Name | Forschungscode | Forschungsphase | Firma | Frühestes Markenname | Frühestes Genehmigungsland | Früheste Indikation | Früheste Genehmigungsgesellschaft | Früheste Genehmigungsdatum | Indikationen | Klinische Studie |
|---|---|---|---|---|---|---|---|---|---|---|
| Methoxy polyethylene glycol-epoetin beta | R-1744; RG-744; RO-0503821; CERA; Ro-50-3821; R-744 | Approved | F. Hoffmann-La Roche Ltd | Mircera | EU | Kidney Failure, Chronic; Anemia | Roche Registration Gmbh | 2007-07-20 | Anemia; Kidney Failure, Chronic; Lung Neoplasms; Renal Insufficiency, Chronic | Details |
| Epoetin beta biosimilar (Veropharm) | Approved | Abbott Laboratories | Vero-epoetin | Anemia | Details | |||||
| Epoetin kappa biosimilar (JCR Pharmaceuticals) | JR-013 | Approved | Jcr Pharmaceuticals Co Ltd | Japan | Anemia | Jcr Pharmaceuticals Co Ltd | 2010-01-20 | Anemia | Details | |
| Darbepoetin alfa biosimilar (Dr Reddy's) | Approved | Dr.Reddy's Laboratories Ltd | Cresp | Anemia | Details | |||||
| Recombinant human erythropoietin alfa (Daewoong Pharmaceutical) | DWP-413 | Approved | Daewoong Pharmaceutical Co Ltd | Eposis | South Korea | Anemia | Daewoong Pharmaceutical Co Ltd | 2007-12-01 | Anemia | Details |
| Recombinant human erythropoietin (3SBio/Biolotus) | Approved | Biolotus, Shenyang Sunshine Pharmaceutical Co Ltd | 益比奥, EPIAO | Mainland China | Anemia | Shenyang Sunshine Pharmaceutical Co Ltd | 1998-01-01 | Anemia | Details | |
| Pegmolesatide | EPO-018B | Approved | Jiangsu Hansoh Pharmaceutical Group Co Ltd | 圣罗莱 | Mainland China | Renal Insufficiency, Chronic; Anemia | Jiangsu Hansoh Pharmaceutical Group Co Ltd | 2023-06-30 | Anemia; Myelodysplastic Syndromes; Renal Insufficiency; Renal Insufficiency, Chronic | Details |
| Epoetin alfa biosimilar (Sotex Farm Firm) | Approved | Protek Group | Eralfon | Anemia | Details | |||||
| Epoetin alfa biosimilar (Amega Bitoech) | Approved | Amega Biotech | Anemia | Details | ||||||
| Epoetin beta biosimilar (Pharmapark) | Approved | Pharmapark | Anemia | Pharmapark | 2007-12-01 | Anemia | Details | |||
| Erythropoietin biosimilar (Fresenius Kabi Oncology) | Approved | Fresenius Kabi Ag | Anemia | Details | ||||||
| Recombinant human erythropoietin (Daying Pharma) | Approved | Daying Pharmaceutical | 诺之素 | Mainland China | Anemia | Daying Pharmaceutical | 2002-05-09 | Anemia | Details | |
| Darbepoetin alfa biosimilar (Torrent) | Approved | Torrent Pharmaceuticals Ltd | Darbatitor | Anemia | Details | |||||
| Recombinant human erythropoietin (CHO Cell), Harbin Pharmaceutical Group Bioengineering | Approved | Harbin Pharmaceutical Group Holding Co Ltd | 雪达升 | Mainland China | Anemia | Harbin Pharmaceutical Group Holding Co Ltd | 2005-10-19 | Anemia | Details | |
| Epoetin beta biosimilar (CinnaGen) | Approved | Cinnagen | CinnaPoietin | India | Anemia | Cinnagen | 2013-01-01 | Anemia | Details | |
| Epoetin theta | Approved | Teva Pharmaceutical Industries Ltd | Biopoin, Eporatio | EU | Kidney Failure, Chronic; Anemia | Teva Gmbh | 2009-10-23 | Anemia; Kidney Failure, Chronic | Details | |
| Epoetin zeta | SB-309 | Approved | Bioceuticals Arzneimittel Ag | Retacrit, Silapo | EU | Kidney Failure, Chronic; Anemia | Stada Arzneimittel Ag | 2007-12-18 | Anemia; Cardio-Renal Syndrome; Kidney Failure, Chronic; Renal Insufficiency | Details |
| Erythropoietin biosimilar (VHB Life Sciences) | Approved | Vhb Life Sciences | Epotop | India | Anemia | Vhb Life Sciences | 2012-01-01 | Anemia | Details | |
| Human erythropoietin biosimilar (Celon Laboratories) | Approved | Celon Laboratories | Celpoietin | India | Anemia | Celon Laboratories | 2012-01-01 | Anemia | Details | |
| Epoetin alfa biosimilar (Probiomed) | Approved | Probiomed | Bioyetin | Mexico | Anemia | Probiomed | 2006-03-01 | Anemia | Details | |
| Epoetin alfa biosimilar (Laboratorios Bioprofarma) | Approved | Laboratorios Bioprofarma | Anemia | Details | ||||||
| Erythropoietin biosimilar (Shantha Biotechnics) | Approved | Shantha Biotechnics Ltd | Shanpoietin | India | Anemia | Shantha Biotechnics Ltd | 2005-01-01 | Anemia | Details | |
| Epoetin alfa biosimilar (Wockhardt) | Approved | Wockhardt Ltd | Wepox | Anemia | Details | |||||
| Darbepoetin alfa biosimilar (JCR Pharmaceuticals/Kissei Pharmaceutical) | JR-131 | Approved | Jcr Pharmaceuticals Co Ltd, Kissei Pharmaceutical Co Ltd | Japan | Anemia | Jcr Pharmaceuticals Co Ltd | 2019-09-20 | Anemia | Details | |
| Recombinant human erythropoietin (Center of Molecular Immunology) | Approved | Center Of Molecular Immunology | Ior | Cuba | Anemia, Aplastic | Center Of Molecular Immunology | 1998-04-01 | Alzheimer Disease; Anemia, Aplastic | Details | |
| Recombinant human erythropoietin (Chengdu Diao Group) | Approved | Chengdu Diao Pharmaceutical Group Co Ltd | 依倍 | Anemia | Details | |||||
| Darbepoetin alfa biosimilar (Hetero Drugs) | Approved | Hetero Drugs Ltd | Actorise | Anemia | Details | |||||
| Epoetin alfa biosimilar (Sedico) | Approved | Sedico | Anemia | Details | ||||||
| Darbepoetin alfa biosimilar (Dong-A ST) | DA-3880; GBS-011(Kidswell Bio) | Approved | Dong-A Pharmaceutical Co Ltd | Japan | Anemia | Sanwa Kagaku Kenkyusho Co Ltd | 2019-09-20 | Anemia; Kidney Diseases | Details | |
| Erythropoietin biosimilar (Neiss Labs) | Approved | Neiss Labs | India | Anemia | Neiss Labs | 2012-08-01 | Anemia | Details | ||
| Erythropoietin biosimilar (Unilab/Biomedis) | Approved | Biomedis, Unilab | Renogen | Anemia | Details | |||||
| Recombinant human erythropoietin (China Resources Angde Biotech Pharma) | Approved | China Resources Angde Biotech Pharma Co Ltd | 佳林豪 | Mainland China | Anemia | China Resources Angde Biotech Pharma Co Ltd | 2003-01-01 | Anemia | Details | |
| Epoetin alfa biosimilar (Biocon) | Approved | Biocon Biopharmaceuticals | Erypro | India | Anemia | Biocon Biopharmaceuticals | 2011-01-01 | Anemia | Details | |
| Epoetin alfa biosimilar (Sandoz) | HX-575 | Approved | Sandoz | Abseamed, Binocrit, Epoetin Alfa Hexal | EU | Kidney Failure, Chronic; Anemia | Hexal Ag | 2007-08-27 | Anemia; Kidney Failure, Chronic; Renal Insufficiency, Chronic | Details |
| Erythropoietin biosimilar (Sudershan Biotech) | Approved | Sudershan Biotech Ltd | Epovin | India | Anemia | Sudershan Biotech Ltd | 2012-01-01 | Anemia | Details | |
| Darbepoetin alfa biosimilar (Chong Kun Dang) | CKD-11101 | Approved | Chong Kun Dang Pharmaceutical Corp | Japan | Anemia | Mylan Nv | 2019-09-20 | Anemia | Details | |
| Erythropoietin biosimilar (Landsteiner Scientific) | Approved | Landsteiner Scientific | Erlan | Mexico | Anemia | Landsteiner Scientific | 2012-08-01 | Anemia | Details | |
| Erythropoietin biosimilar (Klarvoyant Biogenics) | Approved | Klarvoyant | Epomine | Anemia | Details | |||||
| Recombinant human erythropoietin (Beijing Four Rings Bio-Pharmaceutical) | Approved | Beijing Four Rings Bio-Pharmaceutical Co Ltd | 环尔博 | Mainland China | Anemia | Beijing Four Rings Bio-Pharmaceutical Co Ltd | 2000-01-01 | Anemia | Details | |
| Darbepoetin alfa | KRN-321; N-47; Epo-N47 | Approved | Amgen Inc | Aranesp, Nesp, 耐斯宝, Nespo | United States | Anemia | Amgen Inc | 2001-06-08 | Anemia; Brain Injuries, Traumatic; Brain Ischemia; Breast Neoplasms; Carcinoma; Carcinoma, Non-Small-Cell Lung; Cardiovascular Diseases; Diabetes Mellitus; Erythroblastosis, Fetal; Heart Failure; Hematologic Neoplasms; Infant, Newborn, Diseases; Kidney Diseases; Kidney Failure, Chronic; Leukemia, Lymphocytic, Chronic, B-Cell; Liver Diseases; Liver Failure, Acute; Lung Neoplasms; Lymphoma; Multiple Myeloma; Myelodysplastic Syndromes; Neoplasms; Neurodevelopmental Disorders; Prostatic Neoplasms; Renal Insufficiency, Chronic; Small Cell Lung Carcinoma; Solid tumours; Stroke; Trauma, Nervous System; Ventricular Dysfunction | Details |
| Epoetin alfa biosimilar (Blau Farmaceutica) | Approved | Blau Farmaceutica Sa | Eritromax | Brazil | Anemia | Blau Farmaceutica Sa | 2012-01-01 | Anemia; Neoplasms | Details | |
| Epoetin beta biosimilar (Microgen) | Approved | Microgen State Scientific Industrial | Erythrostim | Russian Federation | Anemia | Microgen State Scientific Industrial | 2012-01-01 | Anemia | Details | |
| Recombinant erythropoietin biosimilar (Lupin) | Approved | Lupin Ltd | Epocept | India | Anemia | Lupin Ltd | 2011-01-01 | Anemia | Details | |
| Epoetin alfa biosimilar (Claris Lifesciences) | Approved | Claris Lifesciences Ltd | Epotin | India | Anemia | Claris Lifesciences Ltd | 2011-01-01 | Anemia; Premature Birth | Details | |
| Epoetin alfa biosimilar (Emcure) | Approved | Emcure Pharma | Epofer | Anemia | Details | |||||
| Erythropoietin biosimilar (Center for Genetic Engineering and Biotechnology) | Approved | Center For Genetic Engineering And Biotechnology | Heberitro | Anemia | Details | |||||
| Epoetin alfa biosimilar (Laboratorio Varifarma) | Approved | Laboratorio Varifarma | Anemia | Details | ||||||
| Epoetin alfa (Pooyesh Darou Pharmaceuticals) | Approved | Pooyesh Darou | Iran | Anemia | Pooyesh Darou | 2009-01-01 | Anemia | Details | ||
| Erythropoietin biosimilar (Genius Biotherapeutics) | Approved | Genius Biotherapeutics | Repotin | South Africa | Anemia | Genius Biotherapeutics | 1998-12-01 | Anemia | Details | |
| Recombinant Human Erythropoietin Injection (Shenzhen Saibaoer) | Approved | Shenzhen Sciprogen Bio-Pharmaceutical Co Ltd | 赛博尔 | Mainland China | Anemia | Shenzhen Sciprogen Bio-Pharmaceutical Co Ltd | 2001-01-01 | Anemia | Details | |
| Ephepoetin Alpha | GC-1113; EPO-hyFc; GX-E2; EPO-hFC; EPO-hybrid-Fc; GX-E4 | Approved | Gannex Pharma Co Ltd | Efesa | Indonesia | Anemia | Pt Kalbe Genexine Biologics, Gannex Pharma Co Ltd | 2023-10-23 | Anemia; Renal Insufficiency; Renal Insufficiency, Chronic | Details |
| Epoetin biosimilar (Zydus Cadila) | Approved | Zydus Cadila | Anemia | Details | ||||||
| Epoetin beta | BM-06019; BM-06.019; RO-205-3859 | Approved | F. Hoffmann-La Roche Ltd | NeoRecormon/Epogin, Epogin, Marogen, Recormon, NeoRecormon | EU | Anemia; Kidney Failure, Chronic | Roche Registration Gmbh | 1997-07-16 | Acute Kidney Injury; Anemia; Asphyxia Neonatorum; Cerebral Intraventricular Hemorrhage; Ischemia; Kidney Failure, Chronic; Lymphoma, AIDS-Related; Malaria, Cerebral; Myocardial Ischemia; Renal Insufficiency; Subarachnoid Hemorrhage | Details |
| Recombinant erythropoietin (Cadila Pharmaceuticals) | Approved | Cadila Pharmaceuticals Ltd | Cadicrit | Anemia | Details | |||||
| Epoetin omega | HP-EPO-CRF | Approved | Elanex Pharma Group | Anemia; Bipolar Disorder | Details | |||||
| Recombinant erythropoietin long-acting (Shandong Kexing Bioproducts) | Approved | Shandong Kexing Bio-Products Co Ltd | Yipuding, Eposino, 依普定 | Mainland China | Anemia | Shandong Kexing Bio-Products Co Ltd | 2000-01-01 | Anemia | Details | |
| Recombinant human erythropoietin (Shenzhen Xinpeng Bio-tech) | Approved | Shenzhen Sinobioway Xinpeng Biomedicine Co Ltd | 依博 | Mainland China | Anemia | Shenzhen Sinobioway Xinpeng Biomedicine Co Ltd | 2005-03-29 | Anemia | Details | |
| Epoetin alfa biosimilar (Reliance Life Sciences) | Approved | Genemedix Plc | Epostim, ReliPoietin | Anemia | Details | |||||
| Epoetin alfa biosimilar (LG Life Sciences) | Approved | Lg Chemical Ltd | Espogen | Mainland China | Anemia | Lg Chemical Ltd | 2017-01-01 | Anemia; Brain Ischemia; Cardiovascular Diseases; Cerebral Palsy; Leukemia, Myelomonocytic, Chronic; Myelodysplastic Syndromes | Details | |
| Epoetin alfa biosimilar (Nanogen) | Approved | Nanogen Biopharmaceutical Co | Nanokine | Vietnam | Anemia | Nanogen Biopharmaceutical Co | 2014-01-01 | Anemia | Details | |
| Epoetin alfa biosimilar (Laboratorios AC Farma) | Approved | Laboratorios Ac Farma | Proclat | Anemia | Details | |||||
| Recombinant Erythropoiesis Stimulating Protein Injection (CHO Cell) (3SBio) | RD-01; RD-001; SSS-06 | Approved | Shenyang Sunshine Pharmaceutical Co Ltd | 新比澳 | Mainland China | Anemia | Guangdong Sansheng Pharmaceutical Co Ltd | 2026-03-19 | Anemia; Kidney Failure, Chronic; Neoplasms; Nephrosis; Renal Insufficiency; Renal Insufficiency, Chronic | Details |
| Erythropoietin biosimilar (Incepta Pharmaceuticals) | Approved | Incepta Pharmaceuticals Ltd | Bangladesh | Anemia | Incepta Pharmaceuticals Ltd | 2012-08-01 | Anemia | Details | ||
| Epoetin alfa biosimilar (Biosidus) | Approved | Biosidus | Hemax, Hypercrit | Anemia | Details | |||||
| Erythropoietin biosimilar (RPG Life Sciences) | Approved | Rpg Life Sciences Ltd | Anemia | Rpg Life Sciences Ltd | 2011-01-01 | Anemia | Details | |||
| Epoetin alfa biosimilar (Intas BioPharmaceuticals) | Approved | Intas Biopharmaceuticals | Epofit, Renocel, Erykine | Anemia | Details | |||||
| Epoetin alfa biosimilar (PT Kalbe) | Approved | Kalbe Farma | Indonesia | Anemia | Kalbe Farma | 2003-12-31 | Anemia | Details | ||
| Epoetin alfa biosimilar (CJ Corp) | Approved | HK inno.N Corporation | Epokine | Anemia; Ischemic Attack, Transient; Ischemic Stroke; Moyamoya Disease | Details | |||||
| Recombinant Human Erythropoietin β (CHO Cell)(Shanghai Roche) | Approved | Shanghai Roche Pharmaceuticals Ltd | 罗可曼® Recormon® | Details | ||||||
| Erythropoietin biosimilar (Zuventus Healthcare) | Approved | Zuventus Healthcare | Eporise | India | Anemia | Zuventus Healthcare | 2012-08-01 | Anemia | Details | |
| Recombinant erythropoietin (Shanxi Weiqidaguangming) | Approved | Shanxi Weiqidaguangming Pharmaceutical Co Ltd | Cadicrit | Mainland China | Anemia | Shanxi Weiqidaguangming Pharmaceutical Co Ltd | 1998-01-01 | Anemia | Details | |
| Recombinant erythropoietin biosimilar (Elea) | Approved | Elea | Pronivel | Argentina | Anemia | Elea | 2009-01-01 | Anemia | Details | |
| Recombinant human erythropoietin (CHO Cell), Shanghai Chemo Wanbang Biophama Co Ltd | Approved | Shanghai Kaimao Bio-Pharmaceutical Co Ltd | Mainland China | Anemia | Shanghai Kaimao Bio-Pharmaceutical Co Ltd | 2023-09-28 | Anemia | Details | ||
| Epoetin alfa biosimilar (Dragon Pharmaceutical) | BR-05001 | Approved | Dragon | Anemia | Details | |||||
| Erythropoietin biosimilar (Micro Labs) | Approved | Micro Labs Ltd | India | Anemia | Micro Labs Ltd | 2012-01-01 | Anemia | Details | ||
| Epoetin alfa biosimilar (Fiocruz/Bio-Manguinhos) | Approved | Fundacao Oswaldo Cruz (Fiocruz) | Brazil | Anemia | Fundacao Oswaldo Cruz (Fiocruz) | 2006-12-01 | Anemia | Details | ||
| Epoetin alfa biosimilar (Sun Pharmaceutical Industires) | Approved | Ranbaxy Laboratories | Ceriton | Anemia | Details | |||||
| Epoetin alfa biosimilar (Siam Bioscience) | Approved | Siam Bioscience | Hema-Plus | Thailand | Anemia | Siam Bioscience | 2017-11-01 | Anemia | Details | |
| Recombinant human erythropoietin biosimilar (North China Pharmaceutical Corporation) | JT1801; JT-1801 | Approved | North China Pharmaceutical Company Ltd | 济脉欣 | Mainland China | Anemia | Ncpc Genetech Biotechnology Co Ltd | 2000-01-01 | Anemia; Renal Insufficiency, Chronic | Details |
| Recombinant erythropoietin biosimilar (Recpharma) | Approved | Receptopharm | Epolyrec | Iran | Anemia | Receptopharm | 2015-01-01 | Anemia; Rejection of renal transplantation | Details | |
| Erythropoietin biosimilar (Chalver Laboratorios) | Approved | Chalver Laboratorios | Eritina | Colombia | Anemia | Chalver Laboratorios | 2012-10-01 | Anemia | Details | |
| Erythropoietin (Dong-A ST) | DA-3285 | Approved | Dong-A Pharmaceutical Co Ltd | Eporon | South Korea | Anemia | null | 1999-01-01 | Anemia; Ischemic Stroke | Details |
| Epoetin alfa | KRN-5702 | Approved | Amgen Inc, Johnson & Johnson Innovative Medicine | Espo, 利血宝, Epogen, Epopen, Procrit, Eprex, Erypo, Procrit/Eprex, Globuren, Epoade | United States | Anemia | Amgen Inc | 1989-06-01 | Acquired Immunodeficiency Syndrome; Anemia; Anemia, Neonatal; Arthritis, Rheumatoid; Asphyxia Neonatorum; Brain Diseases; Brain Injuries, Traumatic; Brain Ischemia; Breast Neoplasms; Carcinoma; Cardiac Surgical Procedures; Coronary Artery Disease; Critical Illness; Drug-Related Side Effects and Adverse Reactions; Esophageal Neoplasms; Fatigue; Friedreich Ataxia; Gastrointestinal Neoplasms; Head and Neck Neoplasms; Healthy Aging; Heart Arrest; Heart Defects, Congenital; HIV Infections; Hodgkin Disease; Hypertrophy, Left Ventricular; Hypoplastic Left Heart Syndrome; Infant, Premature, Diseases; Infarction, Middle Cerebral Artery; Intestinal Neoplasms; Kidney Diseases; Kidney Failure, Chronic; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lung Neoplasms; Lymphoma; Lymphoma, Non-Hodgkin; Lymphoproliferative Disorders; Multiple Myeloma; Multiple Trauma; Myelodysplastic Syndromes; Myeloproliferative Disorders; Myocardial Infarction; Neoplasm Metastasis; Neoplasms; N | Details |