DLK1 Molekülinformation
Molecule Name
Protein delta homolog 1
Molekülalias
DLK1,FA1,Protein delta homolog 1,Pg2,Fetal antigen 1
Drug Development Progress
Anzahl der klinischen Arzneimittel2
Anzahl der inverkehr gebrachten Arzneimittel0
Höchste Forschungs- und EntwicklungsphasePhase 1 Clinical
Target-Alias
DLK1，DLK-1，DLK1 protein
Molekülhintergrund
Protein delta homolog 1 is a protein that in humans is encoded by the DLK1 gene. It is expressed as a transmembrane protein, but a soluble form cleaved off by ADAM17 is active in inhibiting adipogenesis, the differentiation of pre-adipocytes into adipocytes.
DLK1 Produktliste
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Klinische Arzneimittelinformation
| Englischer Name | Forschungscode | Forschungsphase | Firma | Indikationen | Klinische Studie |
|---|---|---|---|---|---|
| CBA-1205 | CBA-1205 | Phase 1 Clinical | Chiome Bioscience Inc | Carcinoma, Hepatocellular; Liver Neoplasms; Lung Neoplasms; Melanoma; Neoplasms; Neuroblastoma; Solid tumours | Details |
| ADCT-701 | ADCT-701; ADCT701; LIV-1205 ADC | Phase 1 Clinical | Adc Therapeutics Sa, Cancer Research Technology | Adrenocortical Carcinoma; Carcinoma, Neuroendocrine; Leukemia, Promyelocytic, Acute; Liver Neoplasms; Neuroblastoma; Neuroendocrine Tumors; Small Cell Lung Carcinoma | Details |